The latest court quest by 10 Missouri beer consumers who tried to block InBev’s $52 billion takeover of U.S. beer giant Anheuser-Busch has fallen flat.

The 8th U.S. Circuit Court of Appeals on Wednesday upheld a lower court decision that tossed the group’s antitrust lawsuit. The suit argued the deal would diminish competition and raise beer prices.

The 2008 merger of Belgium-based InBev and St. Louis-based Anheuser-Busch created the world’s largest brewer. Anheuser-Busch, which makes Budweiser, controlled nearly half of the U.S. beer market at the time.

The appeals court suggested that allowing the lawsuit now could be counterproductive to the plaintiffs’ mission.

Anheuser-Busch’s attorneys praised the decision. Messages were left Wednesday with the plaintiffs’ attorneys.