An experimental weight-loss drug made by Vivus Inc. helped obese people lose more than 10 percent of their weight after two years in a clinical trial, but safety details were scant for the drug, which in July was turned down by a panel of U.S. experts.

The company said Tuesday that the second year of a clinical trial found that patients taking the highest dose of its drug, Qnexa, lost an average of 26 pounds, or 11.4 percent of their body weight. Patients taking a placebo had weight loss of 2.5 percent. Get the full story »